Open access · Korean / English

A patient’s difficulties can remain even after a diagnosis is settled.

Some people have seen several specialties yet have not regained daily function; others experience symptoms that vary too much over time and context to be captured by a single test. Alongside continued attention to missed disease, we study lived changes and treatment responses more closely. We read East Asian medical texts and clinical records alongside contemporary research not to repeat inherited answers, but to ask better questions in care today.

Current questions

The questions we are asking first

Research begins by stating questions that matter to patients and clinicians before it announces answers.

Published articles · 2 protocols

Two published articles

The two current publications are research protocols: they set out what will be studied and how, rather than reporting results.

protocolBRC-2026-P0022026-08-12

How Should Persistent Symptoms Not Fully Explained by Diagnosis Be Studied? A Protocol for Scope, Observational Language, and Dual-Track Safety

Some patients continue to experience symptoms and impaired daily function after receiving a diagnosis or completing multiple investigations. These experiences arise in different situations—including residual symptoms of established disease, an evolving differential diagnosis, functional syndromes, and changes after infection or treatment—and should not be collapsed into one cause or a new disorder. This protocol proposes a way to preserve those differences while observing features that diagnostic labels may miss: sequence of onset, symptoms that change together, daily context, loss of function, and response to treatment over time. Two paths remain active. One continues appropriate medical differential diagnosis and reassessment as symptoms, red flags, and trajectories change. The other records patient-important symptoms and function, treatment exposure, and harm without waiting for perfect diagnostic closure. Contemporary research and lived experience are read alongside East Asian primary texts, commentaries and cases, and Korean, Chinese, and Japanese clinical traditions without assuming that their concepts are equivalent. Whether Korean-medicine observations add value must be tested by asking if they improve reproducibility, prediction, or clinical decisions beyond diagnoses and standard measures alone. This is a research design, not a screening tool, treatment recommendation, or efficacy claim.

Yeonseung Choe · Baekrokdam Research Commons (BRC)persistent physical symptoms · diagnostic uncertainty · multisystem symptoms · longitudinal phenotyping
protocolBRC-2026-P0012026-08-12

Allostasis and Korean Medicine Revisited: A Protocol for Mapping Concepts, Measurement, and Translational Hypotheses

This protocol re-examines claims advanced in the 2012 series “Allostasis and Korean Medicine” using contemporary conceptual scholarship, biomedical literature, classical Korean-medicine sources, and counter-evidence. It does not equate Korean-medicine concepts with allostasis; instead, it distinguishes analogy, operational correspondence, mechanistic bridges, and testable translational hypotheses. Only public literature is used, and no treatment recommendation or patient-level conclusion is produced.

Yeonseung Choe · Baekrokdam Research Commons (BRC)allostasis · allostatic load · Korean medicine · evidence map

Collections

Research collections

Founding programme

Symptoms Beyond Diagnostic Boundaries

The founding programme studies persistent, recurrent, multisystem, and time-varying symptoms without turning them into one new disorder, pairing continued diagnostic safety with active research into symptoms, function, and therapeutic possibilities.

Historical reappraisal

Allostasis and Korean Medicine: Reappraisal, 2012–2026

A historical reappraisal of a 2012 multidisciplinary thesis through conceptual history, measurement validity, domain evidence, and explicit counter-hypotheses. It is not the journal’s organising theory.

Research infrastructure

So readers can see where a claim came from

We distinguish editions, translations, and later interpretations, and show which sources support an important sentence and how far that support extends.

How to read our work

Research readers can judge for themselves

The article is written for people; sources, versions, and review records are also available in structured forms that researchers and agents can inspect.

Follow a claim back to its source

Important judgments link to the source and relevant passage so readers can examine the context themselves.

Evidence that does not fit remains visible

We examine contrary findings, alternative explanations, and cases where an idea may not apply—not only material that supports it.

The Korean and English editions say the same thing

Both language editions are managed as one work and checked so translation does not strengthen or weaken the conclusion.

Immediate open access

Full text is available without registration or embargo, with machine-readable discovery, citation, and reuse formats.